He bested the track's old record for the IndyCar series; and rival Scott Dixon - winner of three of the past fives IndyCar races held on the 2.258-mile, 13-turn road course of Mid-Ohio.
Dario Franchitti lines up alongside Power, Dixon is only fifth.
Behind Franchitti and Power are Frenchman Simon Pagenaud and Canadian Alex Tagliani. Although, Tagliani received a 10-place grid penalty for an unapproved engine change that promotes Dixon up to fourth.
James Hinchliffe, the other Canadian, is down in 16th on the grid, where he stands beside Formula One veteran Rubens Barrichello, who qualified one position ahead.
Helio Castroneves, currently runner-up in the championship, suffered both a 10-place grid penalty for another unapproved engine change and a crash in the morning practice session. He will have to start the race with a bruised hand.
Giorgio Pantano, the veteran Italian racer who is standing in for the injured Charlie Kimball, qualified 24th.
Starting grid - IndyCar (Mid-Ohio)
First row
Will Power (Dallara DW12-Chevy) - Penske - 1'05"647 - Fast Six
Dario Franchitti (Dallara DW12-Honda) - Ganassi - 1'05"895 - Fast Six
Second row
Simon Pagenaud (Dallara DW12-Honda) - Schmidt - 1'05"904 - Fast Six
Scott Dixon (Dallara DW12-Honda) - Ganassi - 1'06"097 - Fast Six
Third row
Ryan Briscoe (Dallara DW12-Chevy) - Penske - 1'06"201 - Fast Six
Sebastien Bourdais (Dallara DW12-Chevy) - Dragon - 1'05"941 - Q2
Fourth row
Ryan Hunter-Reay (Dallara DW12-Chevy) - Andretti - 1'06"066 - Q2
Marco Andretti (Dallara DW12-Chevy) - Andretti - 1'06"114 - Q2
Fifth row
Josef Newgarden (Dallara DW12-Honda) - Fisher - 1'06"172 - Q2
Oriol Servia (Dallara DW12-Chevy) - D&R - 1'06"205 - Q2
Sixth row
Justin Wilson (Dallara DW12-Honda) - Coyne - 1'06"661 - Q2
Helio Castroneves (Dallara DW12-Chevy) - Penske - 1'06"704 - Q2
Seventh row
JR Hildebrand (Dallara DW12-Chevy) - Panther - 1'06"377 - Q1
Alex Tagliani (Dallara DW12-Honda) - Herta - 1'06"005 - Fast Six *
Eighth row
Rubens Barrichello (Dallara DW12-Chevy) - KV - 1'06"710 - Q1
James Hinchcliffe (Dallara DW12-Chevy) - Andretti - 1'06"435 - Q1
Ninth row
Mike Conway (Dallara DW12-Honda) - Foyt - 1'06"781 - Q1
Takuma Sato (Dallara DW12-Honda) - Rahal - 1'06"440 - Q1
10th row
Tony Kanaan (Dallara DW12-Chevy) - KV - 1'06"843 - Q1
EJ Viso (Dallara DW12-Chevy) - KV - 1'06"451 - Q1
11th row
James Jakes (Dallara DW12-Honda) - Coyne - 1'07"123 - Q1
Graham Rahal (Dallara DW12-Honda) - Ganassi - 1'06"625 - Q1
12th row
Simona de Silvestro (Dallara DW12-Lotus) - HVM - 1'08"074 - Q1
Giorgio Pantano (Dallara DW12-Honda) - Ganassi - 1'07"035 - Q1
13th row
Ed Carpenter (Dallara DW12-Chevy) - Carpenter - 1'08"512 - Q1 *
10-place grid penalty for unapproved engine change